WASHINGTON: Scientists at Washington University have made a groundbreaking discovery with the development of an exercise pill that could replicate the benefits of exercise without the need for physical activity.
The research, led by Professor Bahaa Elgendy of the university’s Department of Anesthesiology, has resulted in the creation of a compound named SLU-PP-332. This compound activates specialized proteins called estrogen-related receptors (ERRs), which are typically triggered by exercise.
The potential implications of this discovery are vast, as the pill could offer muscle growth, improved performance, and other health benefits associated with exercise. Moreover, it could hold promise in treating conditions such as obesity, muscle atrophy, dementia, heart failure, and declining kidney function.
Benefits of Exercise Pill
Elgendy emphasized the potential of this innovation, particularly for people who are unable to exercise due to various reasons such as age, disease, or physical limitations. He highlighted the possibility of developing therapeutics to address challenging diseases like neurodegenerative conditions and heart failure.
In preclinical trials conducted on mice, the researchers observed promising results. The pills increased the presence of fatigue-resistant muscle fibers and enhanced the endurance of the animals during physical activity. Additionally, the pills demonstrated potential in mitigating damaging processes associated with Alzheimer’s disease and other forms of dementia.
While Elgendy cautioned that the pill is not intended to replace exercise entirely, he underscored its potential to improve the quality of life for persons who face difficulties in engaging in physical activity. He expressed hope that this innovation could benefit those suffering from muscle dystrophy and other debilitating diseases, potentially enhancing their overall well-being.
